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• 15 United States
• 10 France
• 8 Japan
• 7 China
• 5 Korea
• 2 Other

Patent Owner(s)

Patent Owner	Address
VERTEX PHARMACEUTICALS INCORPORATED	50 NORTHERN AVENUE BOSTON MA 02210

International Classification(s)

• C07D:HETEROCYCLIC COMPOUNDS

• [Classification Symbol]

• [Patents Count]

Inventor(s)

Inventor Name	Address	# of filed Patents	Total Citations
ALLEN, Emily Elizabeth	Boston, US	3	0
BANDARAGE, Upul Keerthi	Lexington, US	14	192
BOUCHER, Diane Marie	Beverly, US	6	0
COTTRELL, Kevin Michael	Cambridge, US	32	346
DAMAGNEZ, Veronique	Framingham, US	29	207
DENINNO, Michael Paul	Gales Ferry, US	19	215
FANNING, Lev TD	San Marcos, US	37	873
GALE-DAY, Zachary	Brookline, US	3	0
GARCIA, BARRANTES Pedro Manuel	Melrose, US	4	2
GIROUX, Simon	Cambridge, US	45	459
GU, Wenxin	Concord, US	36	412
HALL, Amy B	Wellesley Hills, US	6	0
HURLEY, Dennis James	San Marcos, US	38	1008
JOHNSON,, Jr Mac Arthur	Derry, US	16	9
KARNS, Alexander S	Boston, US	1	0
LIAO, Yusheng	Lexington, US	35	754
MAXWELL, John Patrick	Hingham, US	34	392
NUHANT, Philippe Marcel	Dorchester, US	11	3
SWETT, Rebecca Jane	Somerville, US	12	2
TANG, Qing	Boxborough, US	82	1559
TAPLEY, Timothy Lewis	Cardiff, US	10	2
THOMSON, Stephen A	Durham, US	13	63
XU, Jinwang	Framingham, US	41	602
ZHANG, Hu	Newton, US	45	140

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Maintenance Fees

Fee	Large entity fee	small entity fee	micro entity fee	due date
3.5 Year Payment	$1600.00	$800.00	$400.00	Nov 25, 2026
7.5 Year Payment	$3600.00	$1800.00	$900.00	Nov 25, 2030
11.5 Year Payment	$7400.00	$3700.00	$1850.00	Nov 25, 2034

Fee	Large entity fee	small entity fee	micro entity fee
Surcharge - 3.5 year - Late payment within 6 months	$160.00	$80.00	$40.00
Surcharge - 7.5 year - Late payment within 6 months	$160.00	$80.00	$40.00
Surcharge - 11.5 year - Late payment within 6 months	$160.00	$80.00	$40.00
Surcharge after expiration - Late payment is unavoidable	$700.00	$350.00	$175.00
Surcharge after expiration - Late payment is unintentional	$1,640.00	$820.00	$410.00

Full Text

US Patent Application No: 2023/0159,521

1H-PYRAZOLO[4,3-G]ISOQUINOLINE AND 1H-PYRAZOLO[4,3-G]QUINOLINE DERIVATIVES AS ALPHA-1-ANTITRYPSIN MODULATORS FOR TREATING ALPHA-1-ANTITRYPSIN DEFICIENCY (AATD)

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