NOVEL PRMT5 INHIBITORS
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United States of America Patent
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Issued Date -
May 25, 2023
app pub date -
Feb 11, 2021
filing date -
Feb 12, 2020
priority date (Note) -
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Abstract
Described herein are compounds of Formula I and pharmaceutically acceptable salt thereof, stereoisomers, tautomers as well as pharmaceutical compositions thereof. Compounds of the present invention are useful for inhibiting PRMT5 activity and may have use in treating proliferative, metabolic and blood disorders. Compounds of Formula I have the following structure: (I)
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