EXOSOME PURIFICATION METHOD AND INTEGRATED DEVICE THEREOF
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United States of America Patent
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Issued Date -
May 18, 2023
app pub date -
Apr 19, 2022
filing date -
Apr 19, 2022
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Abstract
A method exosome purification and characterization is contemplated, comprising the steps of secondary two-stage tangential ultrafiltration to produce an extracted solution, pretreatment of the extracted solution for characterization, characterization of the extracted solution to detect particle size and concentration, and freeze-drying of the extracted solution. An exosome purification integrated device is also contemplated. Through the disclosed methods and devices, exosomes may be better purified and characterized in a manner that results in high practical value to overcome the problems associated with conventional exosome purification processes on the market today, including tedious purification processes, long durations, and high costs.
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