2,5- OR 2,6-DISUBSTITUTED HYDROQUINONE DERIVATIVES WITH AT LEAST ONE CARBOXY, SULFO OR AMIDO GROUP USEFUL AS MEDICAMENTS
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United States of America Patent
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Issued Date -
May 18, 2023
app pub date -
Mar 8, 2021
filing date -
Mar 8, 2021
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Abstract
The present invention provides novel hydroquinone derivatives of formula (I), processes of preparation, as well as pharmaceutical compositions and methods of treating and/or preventing e.g. autoimmune, immunological, rheumatology, vascular disorders, ophthalmologic disorders, fibrotic disorders, metabolic and gastrointestinal disorders, neuroinflammatory and neurodegenerative diseases, neoplasms and cancer associated disorders, hormone related diseases and immunological disorders resulting from viral and bacterial infectious diseases and complications thereof. wherein R1 is COOR4, (CH2)nCOOR4, SO3H, (CH2)nSO3H or CONH—R10; one of R2 and R3 is H and the other is R5.
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