METHODS FOR ENHANCING VASCULAR DENSITY
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United States of America Patent
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Issued Date -
May 18, 2023
app pub date -
Jan 20, 2023
filing date -
Jan 20, 2023
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Abstract
The present invention relates to methods of increasing vascular density and/or blood flow in tissue of a subject, and to increasing exercise capacity of a subject, the methods include administering to a subject an effective amount of an agent that elevates SIRTI activity in endothelial cells of the subject, the invention further includes administering an NAD+ agonist or NAD+ precursor to a subject to increase vascular density and/or blood flow. The invention includes compositions comprising the said agent.
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