MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS

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United States of America Patent

APP PUB NO 20230127655A1
SERIAL NO

17692235

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Compounds of the present invention and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”). The present invention also relates to methods of treating ABC transporter mediated diseases using compounds of the present invention.

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Patent Owner(s)

Patent OwnerAddress
VERTEX PHARMACEUTICALS INCORPORATEDCAMBRIDGE MA

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
BEAR, Brian Richard Carlsbad, US 34 1388
GROOTENHUIS, Peter Diederik Jan San Diego, US 56 2381
HADIDA, RUAH Sara Sabina La Jolla, US 56 618
McCARTNEY, Jason Cardiff by the Sea, US 117 5979
MILLER, Mark Thomas San Diego, US 70 1507
NUMA, Mehdi Michel Djamel San Diego, US 24 1546
VAN, GOOR Fredrick F San Diego, US 52 3229
ZHOU, Jinglan San Diego, US 150 8232

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