Ketoreductase mutant and method for producing chiral alcohol

Number of patents in Portfolio can not be more than 2000

United States of America Patent

APP PUB NO 20220403421A1
SERIAL NO

17774891

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

Disclosed are a ketoreductase mutant and a method for producing a chiral alcohol. The ketoreductase mutant has an amino acid sequence obtained by the mutation of the amino acid sequence shown in SEQ ID NO: 1, and the mutation includes a mutation siteK200H. In the present disclosure, the mutant obtained by mutation takes a ketone compound as a raw material, the chiral alcohol may be efficiently produced by stereoselective reduction, and the stability is greatly improved, which is suitable for popularization and application to the industrial production of the chiral alcohol.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddress
ASYMCHEM LABORATORIES (FUXIN) CO LTDNO 90 DEVELOPMENT AVENUE HIGH-TECH INDUSTRIAL DEVELOPMENT ZONE FUXIN LIAONING 123000

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
HONG, Hao Morrisville, US 68 12
HSIAO, Yi Tianjin, CN 11 31
JAMES, Gage Morrisville, US 32 9
JIAO, Xuecheng Tianjin, CN 17 0
WANG, Xiang Tianjin, CN 215 1154
YANG, Yiming Tianjin, CN 24 77
ZHANG, Kejian Tianjin, CN 17 38
ZHANG, Na Tianjin, CN 248 911
ZHANG, Yanqing Tianjin, CN 34 140

Cited Art Landscape

Load Citation

Patent Citation Ranking

Forward Cite Landscape

Load Citation