IONIZABLE AMINE LIPIDS AND LIPID NANOPARTICLES
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United States of America Patent
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Issued Date -
Dec 22, 2022
app pub date -
Apr 24, 2020
filing date -
Apr 24, 2020
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Abstract
The disclosure provides ionizable amine lipids and salts thereof (e.g., pharmaceutically acceptable salts thereof) useful for the delivery of biologically active agents, for example delivering biologically active agents to cells to prepare engineered cells. The ionizable amine lipids disclosed herein are useful as ionizable lipids in the formulation of lipid nanoparticle-based compositions.
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