THREE-DIMENSIONAL MICROELECTRODE ARRAY HAVING ELECTRICAL AND MICROFLUIDIC INTERROGATION OF ELECTROGENIC CELL CONSTRUCTS
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United States of America Patent
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Issued Date -
Dec 22, 2022
app pub date -
Jun 6, 2022
filing date -
Jun 6, 2022
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Abstract
A three-dimensional (3D) microelectrode array for in vitro electrical and microfluidic interrogation of electrogenic cell constructs includes a substrate having a plurality of micro vias. A hypodermic microneedle is received within each micro via of a first subgroup of the plurality of micro vias and each has a length that exceeds the thickness of the substrate to form a hypodermic microneedle array on the top face of the substrate. Metallic traces are formed on the bottom face and interconnect the hypodermic microneedles. A culturing area is formed in the top face.
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