METHODS FOR TREATING PATIENTS HAVING CFH MUTATIONS WITH RECOMBINANT CFH PROTEINS

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United States of America Patent

APP PUB NO 20220395557A1
SERIAL NO

17771334

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Abstract

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The present disclosure provides methods for treating, preventing, or inhibiting diseases in patients having one or more mutations in complement factor H (CFH), complement component 3 (C3), and complement factor B (CFB). Also provided are combination therapies comprising a CFH protein and a VEGF antagonist for treating neovascularization-associated ocular diseases.

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Patent Owner(s)

Patent OwnerAddress
GEMINI THERAPEUTICS INCONE KENDALL SQUARE BUILDING 300 CAMBRIDGE MA 02139

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Huang, Lisa Cambridge, US 9 12
Katti, Suresh Hamden, US 4 0
Lauder, Scott Andover, US 11 199
McLaughlin, James Cambridge, US 34 173

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