DNA aptamers and use thereof for the treatment of cancer

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United States of America Patent

PATENT NO 12077760
APP PUB NO 20220380766A1
SERIAL NO

17413550

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Abstract

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Provided herein are DNA aptamers targeting AXL receptor kinase. The DNA aptamers may comprise a thiophosphate backbone and be chemically modified. Further provided herein are methods of use thereof for the treatment of a disease or disorder, such as cancer.

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Patent Owner(s)

Patent OwnerAddress
BOARD OF REGENTS THE UNIVERSITY OF TEXAS SYSTEM210 WEST 7TH STREET AUSTIN TX 78701

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Amero, Paola Houston, US 2 0
De, Franciscis Vittorio Naples, IT 12 94
Lopez-Berestein, Gabriel Houston, US 54 1103
Mitra, Rahul Houston, US 14 48
Rao, Lokesh Ganesh L Houston, US 1 0
Rodriguez-Aguayo, Cristian Houston, US 1 0
Sood, Anil K Houston, US 18 201
Volk, David Houston, US 10 406

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