5'-MODIFIED NUCLEOSIDE AND NUCLEOTIDE USING SAME

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United States of America Patent

APP PUB NO 20220372060A1
SERIAL NO

17427134

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Disclosed are a 5′-modified nucleoside and a nucleotide using the same. The nucleoside of the present invention is represented by the formula (I) below. The 5′-modified nucleoside of the present invention is usable as a substitute for a phosphorothioate-modified nucleic acid, which has a risk of, for example, accumulation in a specific organ. The 5′-modified nucleoside also has excellent industrial productivity because a diastereomer separation step is not involved in the production process thereof.

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Patent Owner(s)

Patent OwnerAddress
OSAKA UNIVERSITYOSAKA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
HABUCHI, Takaki Osaka, JP 4 1
INOUE, Takao Osaka, JP 204 3324
KATO, Go Osaka, JP 43 213
OBIKA, Satoshi Osaka, JP 50 1737
SUGIURA, Takaya Osaka, JP 2 0
YAMAGUCHI, Takao Osaka, JP 197 4627
YOSHIDA, Tokuyuki Osaka, JP 6 3

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