A SERS METHOD FOR ANALYZING A VISCOUS BIOFLUID

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United States of America Patent

APP PUB NO 20220349902A1
SERIAL NO

17762760

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Abstract

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The invention relates to a SERS method for analyzing a biological sample, the method comprising the following step of: a. obtaining a biological sample which is viscous biofluid, b. depositing at least one droplet of the biological sample onto a microscope slide, and drying the droplet, c. depositing a drop of an aqueous dispersion of metallic nanoparticles above the droplet dried in step b), to have a dense distribution of nanoparticles on the surface of the dried droplet and to obtain a SERS-activated biological sample, d. drying the SERS-activated biological sample, e. irradiating the SERS-activated biological sample using a light source to obtain a SERS spectrum, and f. collecting the SERS spectrum.

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Patent Owner(s)

Patent OwnerAddress
ASSISTANCE PUBLIQUE-HOPITAUX DE PARIS3 AVENUE VICTORIA PARIS F-75004
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE15 QUAI ANATOLE-FRANCE 75700 PARIS
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALEA CORP OF FRANCE 101 RUE DE TOLBIAC F-75654 PARIS
UNIVERSITE DE REIMS CHAMPAGNE-ARDENNE2 AVENUE ROBERT SCHUMAN REIMS CEDEX 51724
UNIVERSITÉ PARIS CITÉ85 BOULEVARD SAINT-GERMAIN PARIS 75006

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
BORDERIE, Didier Paris, FR 3 0
ETIENNE, François Rouen, FR 1 0
GOBINET, Cyril Athies-sous-Laon, FR 3 6
MANGENEY, Claire Villejuif, FR 1 0
NGUYEN, Christelle Paris, FR 1 0
PIOT, Olivier Cormontreuil, FR 3 6
RANNOU, François Paris, FR 3 0
ROBINSON, Amanda Le Kremlin-Bicêtre, FR 3 20

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