A Chemo-Enzymatic Process for the Preparation of Homopropargylic Alcohol

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United States of America Patent

APP PUB NO 20220333139A1
SERIAL NO

17621052

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Abstract

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The present invention relates to an enzymatic process for preparation of optically pure enantiomers of homopropargylic alcohol compounds of formula I, which are useful intermediates for the synthesis of Halichondrin B and analogs. wherein, P is H or an alcohol protecting group, n is an integer ranging from 0-12.

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Patent Owner(s)

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COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCHANUSANDHAN BHAWAN RAFI MARG NEW DELHI 110001

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
CHANDRASEKHAR, Srivari Telangana, IN 7 1
GHOSH, Subhash Telangana, IN 2 0
KRISHNA, Avula Shiva Telangana, IN 1 0
MAINKAR, Prathama Satyendra Telangana, IN 6 1
NASAM, Rajesh Telangana, IN 1 0
PABBARAJA, Srihari Telangana, IN 6 2
REDDY, Chada Raji Telangana, IN 2 0
SUDHAKAR, Gangarajula Telangana, IN 3 0
THENKRISHNAN, Kumaraguru Telangana, IN 1 0

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