METHOD FOR PREPARING CONTROLLED PEPTIDE-BASED POLYMERS AND COPOLYMERS IN AN AQUEOUS SOLUTION
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United States of America Patent
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Oct 13, 2022
app pub date -
Sep 3, 2020
filing date -
Sep 3, 2019
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Abstract
The present invention relates to a “one-pot” method for preparing an aqueous solution of nanoparticles with amphiphilic block copolymers and comprising polypeptide units, the method comprising at least one step (E1), in an aqueous solvent, consisting of bringing together: —at least one hydrophilic polymer (P1) comprising at least one amine function, and —at least one hydrophobic α-amino acid N-carboxyanhydride monomer.
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