Therapeutic Antibodies Against Osteopontin

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United States of America Patent

APP PUB NO 20220324956A1
SERIAL NO

17633797

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Therapeutic antibodies specific for osteopontin and methods of using them for treating osteopontin-associated disorders are provided. In particular, antibodies, or antigen-binding fragments thereof, that inhibit thrombin-cleavage of osteopontin or block the activity of thrombin cleavage fragments of osteopontin are provided. Additionally, antibody conjugates and pharmaceutical compositions or formulations comprising the antibodies or antibody conjugates as well as kits including the antibodies, conjugates, or formulations are also provided.

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Patent Owner(s)

Patent OwnerAddress
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITYSTANFORD CA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Leung, Lawrence LK Hillsborough, US 3 0
Morser, Michael J San Francisco, US 10 139
Myles, Timothy Sunnyvale, US 8 3

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