COMPOSITIONS OF EXOSOMES AND AAV
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United States of America Patent
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Issued Date -
Oct 13, 2022
app pub date -
Apr 17, 2020
filing date -
Apr 17, 2019
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Abstract
The present disclosure relates to extracellular vesicles, e.g., exosomes, comprising an AAV and a scaffold protein. In some aspects, the AAV is in the lumen of the extracellular vesicle. In some aspects, the AAV is associated with the luminal surface of the extracellular vesicle. In some aspects, the AAV is associated with the exterior surface of the extracellular vesicle. Also provided herein are methods for producing the exosomes and methods for using the exosomes to treat and/or prevent diseases or disorders.
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