METHODS AND SYSTEMS FOR PREPARING THERAPEUTIC SOLUTIONS FOR POLYMICROBIAL INFECTIONS
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United States of America Patent
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Oct 6, 2022
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Jun 1, 2022
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Apr 19, 2017
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Abstract
Methods for identifying and providing therapeutic solutions for treating polymicrobial infections, such as but not limited to urinary tract infections, based on concordance between ABR genes and antibiotic susceptibility. The methods herein feature detection and identification of organisms of the polymicrobial infection, phenotypic pooled sensitivity tests for determining the susceptibility or resistance of the polymicrobial infection in the sample to an antibiotic or other therapeutic agent, and identification of resistance genes, e.g., genetic markers that may indicate resistance to a particular treatment. Together, the data can be applied against databases of antibiotic/therapeutic susceptibility or resistance for particular known polymicrobial infections in order to provide one or more therapeutic solutions for the polymicrobial infection.
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