METHODS OF TREATING CRYPTOCOCCUS INFECTIONS
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United States of America Patent
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Issued Date -
Oct 6, 2022
app pub date -
Aug 13, 2020
filing date -
Aug 13, 2019
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Abstract
The present disclosure is directed to a method of treating or preventing a fungal infection in a subject including a Cryptococcus spp., which method includes an induction treatment phase and a consolidation treatment phase, wherein the induction treatment phase includes: administering amphotericin B (cAMB) and 5-Flucytosine or an azole to the subject, wherein the cAMB and the 5-Flucytosine or the azole are mucosally administered. cAMB formulations are also disclosed.
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