Multi-perspective microscopic imaging guided microinjection of microscopic objects across large field of views

Number of patents in Portfolio can not be more than 2000

United States of America

PATENT NO 12094161
APP PUB NO 20220309705A1
SERIAL NO

17656130

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Abstract

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Techniques are described for automated microinjection of substances, such as genetic material, into microscopic objects, such as embryos. An example system includes a pressure controller, a stereoscopic imaging apparatus, a first camera, a second camera, and a computing system. The computing system is configured to apply one or more computer vision algorithms that determine, based on image data generated by the stereoscopic imaging apparatus, first camera, and second camera, a location of a tip of a micropipette and a location of a particular microscopic object in three-dimensional space. The computing system is further configured to control the pressure controller to cause the micropipette to eject the substance from the tip of the micropipette and into the particular microscopic object.

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Patent Owner(s)

Patent OwnerAddress
REGENTS OF THE UNIVERSITY OF MINNESOTA600 MCNAMARA ALUMNI CENTER 200 OAK STREET SE MINNEAPOLIS MN 55455-2020

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Alegria, Andrew Minneapolis, US 11 144
Auch, Benjamin Saint Paul, US 2 2
Gohl, Daryl M Minneapolis, US 4 3
Joshi, Amey S Minneapolis, US 2 2
Kodandaramaiah, Suhasa B St Paul, US 4 5

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