TREATMENT OF KIDNEY DISEASES ASSOCIATED WITH ELEVATED AVP
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United States of America Patent
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Issued Date -
Aug 25, 2022
app pub date -
May 2, 2022
filing date -
Jan 31, 2017
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Abstract
Disclosed are the methods for treating kidney disease including autosomal dominant polycystic kidney disease (ADPKD) in a subject, comprising the step of administering to the subject a composition comprising a therapeutically effective amount of ticagrelor or a derivative thereof, treating ADPKD. Disclosed are methods of decreasing arginine vasopressin (AVP) production in a subject comprising the step of administering to the subject a composition comprising an effective amount of ticagrelor, thereby decreasing AVP production. Disclosed are methods for treating dilutional hyponatremia in a subject comprising the step of administering to the subject a composition comprising an effective amount of ticagrelor, thereby decreasing AVP production.
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