ANTI-MUTATION TYPE FGFR3 ANTIBODY AND USE THEREFOR
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United States of America Patent
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Issued Date -
Aug 25, 2022
app pub date -
Jul 10, 2020
filing date -
Jul 12, 2019
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Abstract
The present disclosure provides antibodies capable of distinguishing between wild-type FGFR3 and FGFR3 S249C mutants. Using these antibodies, antigen-binding molecules capable of selectively damaging tumor cells expressing an FGFR3 S249C mutant were constructed.
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