Di-Isopropyl-Phosphinoyl -Alkanes as topical agents for the treatment of sensory discomfort

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United States of America Patent

APP PUB NO 20220265687A1
SERIAL NO

17803311

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Abstract

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The present discovery pertains generally to the field of therapeutic compounds. More specifically the present discovery pertains to certain di-isopropyl-phosphinoyl-alkanes as described herein, DIPA-1-7, DIPA-1-8, and DIPA-1-9, collectively referred to herein as “DIPA compounds”, that are useful, for example, in the treatment of the discomforts of dermatological disorders (e.g., diseases) The treatment is for the dysesthesia (e.g., caused by irritation, itch, or pain) due to dermatitis, urticaria; scalp itch; vulvar itch; lichen sclerosus; cholestatic itch; psoriasis; sebhorrheic dermatitis; allergic conjunctivitis; blepharitis; and pruritus of the elderly. The applicant has found that topical delivery of DIPA compounds to the skin alleviates the dysesthesia of these conditions in human subjects. The present discovery pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, for example, in the treatment of the dysesthesia of these dermatological disorders.

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Patent Owner(s)

Patent OwnerAddress
IVIEW THERAPEUTICS INC5 CEDAR BROOK DRIVE SUITE 2 CRANBURY NJ 08512

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Wei, Edward T Berkeley, US 46 329

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