ANTI-PD-L1 ANTIBODY

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United States of America Patent

APP PUB NO 20220227871A1
SERIAL NO

17579517

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention provides an anti-PD-L1 antibody capable of repeated administration even to animals other than rat. An anti-PD-L1 antibody comprising (a) a light chain comprising a light chain variable region containing CDR1 having the amino acid sequence of QSLLYSENQKDY (SEQ ID NO: 37), CDR2 having the amino acid sequence of WAT and CDR3 having the amino acid sequence of GQYLVYPFT (SEQ ID NO: 38) and the light chain constant region of an antibody of an animal other than rat; and (b) a heavy chain comprising a heavy chain variable region containing CDR1 having the amino acid sequence of GYTFTSNF (SEQ ID NO: 39), CDR2 having the amino acid sequence of IYPEYGNT (SEQ ID NO: 40) and CDR3 having the amino acid sequence of ASEEAVISLVY (SEQ ID NO: 41) and the heavy chain constant region of an antibody of an animal other than rat. A pharmaceutical composition comprising the above anti-PD-L1 antibody as an active ingredient. A method for preparing the above anti-PD-L1 antibody is also provided.

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Patent Owner(s)

Patent OwnerAddress
NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITYKITA 8-JYO NISHI 5-CHOME KITA-KU SAPPORO-SHI HOKKAIDO 0600808 ?0600808

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Konnai, Satoru Sapporoshi, JP 9 2
Maekawa, Naoya Sapporoshi, JP 11 10
Murata, Shiro Sapporoshi, JP 20 109
Nakajima, Chie Sapporoshi, JP 10 2
Nishimori, Asami Sapporoshi, JP 8 2
Ohashi, Kazuhiko Sapporoshi, JP 27 190
Okagawa, Tomohiro Sapporoshi, JP 9 2
Suzuki, Yasuhiko Sapporoshi, JP 84 829

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