COMPOSITIONS AND METHODS TO BLOCK AND BIND CCR2 TO MODULATE CELLULAR FUNCTION
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United States of America Patent
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Jul 14, 2022
app pub date -
May 13, 2020
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May 13, 2019
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Abstract
Provided herein are single chain variable fragment antibodies that are directed against N-terminal or extracellular loop regions of CCR2. The scFvs can be used alone or in combination to modify macrophage number and migration and to reduce the growth of tumors.
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