BIOMARKER FOR RHEUMATOID ARTHRITIS TREATMENT

Number of patents in Portfolio can not be more than 2000

United States of America

APP PUB NO 20220205980A1
SERIAL NO

17601908

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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An object of the present invention is to provide a method for predicting a therapeutic effect of a drug that inhibits FKN-CX3CR1 interaction on rheumatoid arthritis in a rheumatoid arthritis subject, and novel and more effective therapeutic agent for rheumatoid arthritis exploiting the method. In order to predict a therapeutic effect of a drug that inhibits fractalkine (FKN)-CX3CR1 interaction in a rheumatoid arthritis subject, provided is a method comprising predicting the therapeutic effect of the drug in the subject on the basis of a measurement value of CD16+ monocytes in a biological sample obtained from the subject before the start of administration of the drug.

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Patent Owner(s)

Patent OwnerAddress
EISAI R&D MANAGEMENT CO LTD6-10 KOISHIKAWA 4-CHOME BUNKYO-KU TOKYO 112-8088

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hojo, Seiichiro Bunkyo-ku, Tokyo, JP 1 0
Imai, Toshio Kobe-shi, Hyogo, JP 54 303
Tago, Fumitoshi Bunkyo-ku, Tokyo, JP 2 0
Yamada, Tomohiro Kobe-shi, Hyogo, JP 140 1255
Yasuda, Nobuyuki Kobe-shi, Hyogo, JP 65 1499

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