Molecular Barcode Analysis by Single-Molecule Kinetics
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United States of America Patent
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Issued Date -
Jun 16, 2022
app pub date -
Dec 15, 2021
filing date -
Dec 15, 2021
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Abstract
Aspects of the disclosure provide methods of determining molecular barcode content based on binding interactions between a barcode recognition molecule and a molecular barcode. In some aspects, the disclosure relates to methods comprising contacting a molecular barcode with a barcode recognition molecule that binds to one or more sites on the molecular barcode, detecting a series of signal pulses, and determining the barcode content based on a barcode-specific pattern in the series of signal pulses.
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