LIPIDIC ANALOGS OF ANTI-CANCER STEM CELL AGENT
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Jun 2, 2022
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Mar 6, 2020
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Mar 6, 2020
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Abstract
A group of specific sulfated flavonoid agents carrying cholesterol modification display promising in vivo anti-cancer activity through selective inhibition of cancer stem cells, and not of adult or hematopoietic stem cells. The compounds exhibit high potency, excellent oral bioavailability and a physiologically relevant therapeutic window.
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