USE OF LOW PH AND DEXTRAN SULFATE DURING HARVEST TREATMENT FOR PROTEIN PURIFICATION
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United States of America Patent
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Issued Date -
May 26, 2022
app pub date -
Feb 8, 2022
filing date -
Feb 8, 2022
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In certain embodiments, the invention provides a method of purifying a protein of interest from a mixture which comprises the protein of interest and one or more contaminants, comprising: (a) contacting the mixture with a dextran polymer under conditions suitable for the dextran polymer to bind to one or more contaminants, thereby to form a contaminant precipitate; (b) separating the contaminant precipitate from the mixture to form a solution, thereby purifying the protein of interest.
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