Cryoprotective Compositions and Methods for Protection of a Surgical Site During Cryosurgery

Number of patents in Portfolio can not be more than 2000

United States of America

APP PUB NO 20220087250A1
SERIAL NO

17482898

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A cryoprotective composition configured to be applied during cryotreatment of a patient includes at least one biodegradable and/or bioerodible fluid agent and at least one non-toxic cryoprotectant agent. A therapeutically effective amount of the cryoprotective composition deposited in a body space of the patient in proximity to the cryotreatment remains within at least a portion of the body space for a duration of the cryotreatment. At least a portion of a body tissue proximate to the body space is viable after the cryotreatment. A method of protecting a surgical site during prostate cryosurgery is also provided. The method includes injecting a therapeutically effective amount of the cryoprotective composition into the body space, wherein the body space is a periprostatic space of a patient.

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Patent Owner(s)

Patent OwnerAddress
REGENTS OF THE UNIVERSITY OF MINNESOTA200 OAK STREET SE SUITE 600 MCNAMARA ALUMNI CENTER MINNEAPOLIS MN 55455

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bischof, John St. Paul, US 8 8
Iaizzo, Paul A White Bear Lake, US 29 809
Ramirez, David A St. Paul, US 6 25
Ranjbartehrani, Pegah Falcon Heights, US 2 6
Schmidlin, Franz Geneva, CH 2 6
Shao, Qi Plymouth, US 7 20

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