TRANSPLANTATION OF MITOCHONDRIA INTO LYMPHOID ORGAN AND COMPOSITION THEREFOR

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United States of America

APP PUB NO 20220031743A1
SERIAL NO

17275983

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Abstract

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Provided herein are a method for isolation and transplantation of intact mitochondria to a lymphoid organ (a primary lymphoid tissue or a secondary lymphoid tissue), a composition of cells prepared by using a method described herein, and a method for manufacturing cells described herein. In particular, provided herein are methods of isolating intact mitochondria from a donor cell. Also provided herein are methods of transplanting mitochondria into a recipient cell. In some aspects, the methods can be performed in vivo. Further provided are a composition of cells that include the cells prepared using the methods of the present invention.

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Patent Owner(s)

Patent OwnerAddress
LUCA SCIENCE INCTOKYO JAPAN TOKYO METROPOLIS

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
HARASHIMA, Hideyoshi Hokkaido, JP 44 105
SASAKI, Daisuke Hokkaido, JP 204 857
SUGANUMA, Masashi Aichi, JP 31 221
YAMADA, Yuma Hokkaido, JP 6 1
YOKOTA, Takafumi Osaka, JP 1 0

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