HIGH-EFFICIENCY TRANSFECTION OF BIOLOGICAL CELLS USING SONOPORATION
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United States of America
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Jan 27, 2022
app pub date -
Oct 8, 2021
filing date -
Oct 8, 2021
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Abstract
A method is provided for achieving transfection of host cells using sonoporation. An acoustic radiation generator is positioned in acoustic coupling relationship with respect to a reservoir containing host cells to be transfected, exogenous material to be incorporated into the host cells, and a cell-compatible fluid medium. The acoustic radiation generator is activated to generate acoustic radiation and direct the acoustic radiation into the reservoir in a manner effective to enable transfection of the host cells with the exogenous material.
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