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• 15 United States
• 10 France
• 8 Japan
• 7 China
• 5 Korea
• 2 Other

Patent Owner(s)

Patent Owner	Address
PSIGRYPH INC	450 EASTBRIDGE BLVD WATERLOO ONTARIO N2K 3Y4

International Classification(s)

• D01C:CHEMICAL TREATMENT OF NATURAL FILAMENTARY OR FIBRO....
• A61K:PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOS....
• A23L:FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT....
• A61Q:USE OF COSMETICS OR SIMILAR TOILET PREPARATIONS

• 2019 Application Filing Year
• D01C Class
• 7 Applications Filed
• 2 Patents Issued To-Date
• 28.58 % Issued To-Date

Inventor(s)

Inventor Name	Address	# of filed Patents	Total Citations
CHANDRASEKARAN, Renu	Brampton, Ontario, CA	1	0
# of filed Patents : 1 Total Citations : 0
CORREA-BETANZO, Julieta	Toronto, Ontario, CA	2	0
# of filed Patents : 2 Total Citations : 0
PADMANABHAN, Priya	Waterloo, Ontario, CA	4	9
# of filed Patents : 4 Total Citations : 9
PALIYATH, Gopinadhan	Waterloo, Ontario, CA	5	14
# of filed Patents : 5 Total Citations : 14
SUBRAMANIAN, Jayasankar	St. Catherines, Ontario, CA	9	29
# of filed Patents : 9 Total Citations : 29
TIWARI, Krishnaraj	Mont Royal, Québec, CA	3	0
# of filed Patents : 3 Total Citations : 0

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• 0 Citation Count
• D01C Class

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Full Text

US Patent Application No: 2013/0281,513

siRNA FOR INHIBITION OF Hif1alpha EXPRESSION AND ANTICANCER COMPOSITION CONTAINING THE SAME

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Abstract

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Disclosed are small interfering RNA (siRNA) that complementarily binds to a base sequence of Hif1α mRNA transcript, thereby inhibiting expression of Hif1α without inducing immune responses, and a use of the siRNA for prevention and/or treatment of cancer. Since Hif1α is commonly overexpressed in almost all cancer cells, the siRNA that complementarily binds to Hif1α-encoding mRNA may inhibit expression of Hif1α through RNA-mediated interference (RNAi), thereby inhibiting proliferation and metastasis of cancer cells, and thus, the siRNA may be useful as an anticancer agent.

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Description

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