NON-REPLICATING VIRUS-DERIVED PARTICLES AND USES THEREOF
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United States of America Patent
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Nov 11, 2021
app pub date -
Jul 21, 2021
filing date -
Dec 21, 2012
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There is described herein a non-replicating Rhabdovirus-derived particle that lacks the ability to spread between cells while having tropism against immortalized cells. The non-replicating Rhabdovirus-derived particle may have cytolytic tropism against immortalized cells. There is also described a non-replicating Rhabdovirus-derived particle that lacks the ability to spread between cells but has innate and/or adaptive immune-stimulating properties.
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