COMPOSITIONS AND METHODS OF ENHANCING 5-HYDROXYTRYPTOPHAN BIOAVAILABILITY
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United States of America Patent
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Nov 11, 2021
app pub date -
Jan 28, 2019
filing date -
Jan 29, 2018
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Provided are methods of enhancing bioavailability of enterally administered 5-hydroxytryptophan (5-HTP) in a subject in need thereof, said method comprising enterally co-administering low-dose carbidopa with said 5-HTP, as well as pharmaceutical formulations useful for the same. In some embodiments, the 5-HTP and/or low-dose carbidopa are provided as slow-release formulation(s).
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