Compositions and methods for enhancing the stability of transgenes in poxviruses

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United States of America Patent

PATENT NO 11654189
APP PUB NO 20210338788A1
SERIAL NO

17367528

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Abstract

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Provided herein are recombinant poxviruses that are stable through successive passaging of the recombinant poxviruses. More particularly, the recombinant poxviruses comprise one or more modified nucleic acids encoding MUC1, CEA, and/or TRICOM antigens, wherein the recombinant poxviruses are stable through successive passaging. Also, provided herein are compositions and method related thereto.

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Patent Owner(s)

  • BAVARIAN NORDIC A/S

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Dirmeier, Ulrike Starnberg, DE 10 18
Kalla, Markus Penzberg, DE 16 26
Rountree, Ryan San Mateo, US 9 74

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