HIGH CONCENTRATION FORMULATIONS

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United States of America Patent

APP PUB NO 20210338707A1
SERIAL NO

17377972

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Low-viscosity, high concentration nucleic acid compositions that can be administered by multiple parenteral routes may allow for less frequent dosing than nucleic acid products currently on the market. In particular, low-viscosity defibrotide formulations for subcutaneous, intramuscular, and intraperitoneal administration are more convenient to the patient and/or are administered outside of the hospital setting. Formulations of the invention may be used for the treatment of numerous conditions including for example, treatment of peripheral arteriopathies, treatment of acute renal insufficiency, treatment of acute myocardial ischemia, and treatment and prevention of sinusoidal obstruction syndrome or VOD.

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Patent Owner(s)

Patent OwnerAddress
JAZZ PHARMACEUTICALS IRELAND LIMITEDONE BURLINGTON ROAD FOURTH FLOOR CONNAUGHT HOUSE DUBLIN 4

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
BENNETT, William J Turnersville, US 5 37
DIMITROVA, Mariana Wallingford, US 8 39
WANG, Qi Pennington, US 814 5281

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