Platinum-acridine compounds and methods of treating cancers

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United States of America Patent

PATENT NO 12023341
APP PUB NO 20210330679A1
SERIAL NO

17235382

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Abstract

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Platinum-acridines and analogs thereof as cytotoxic agents for cancer treatment. Also provided methods of using hMATE1 (SLC47A1) as a biomarker to identify tumors that are likely to respond to the agents, and epigenetically sensitizing tumor tissue to anticancer drugs targeting this membrane transporter.

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WAKE FOREST UNIVERSITY391 TECHNOLOGY WAY SUITE 199 WINSTON-SALEM NC 27101

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bierbach, Ulrich Winston-Salem, US 13 38
Mancera-Ortiz, Ikeer Y High Point, US 1 0
Watkins, Noah H Lewisville, US 2 0
Yao, Xiyuan Winston-Salem, US 3 1
Zhang, Shenjie Winston-Salem, US 2 0

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