Cocrystal of progesterone and preparation method and use thereof

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United States of America Patent

PATENT NO 11866459
APP PUB NO 20210277049A1
SERIAL NO

17191769

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Abstract

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The present invention relates to a cocrystal of progesterone, which is formed by the active ingredient progesterone and a cocrystal former which is selected from isophthalic acid, 4-formylbenzeneboronic acid and 3-nitrophthalic acid. The present invention also relates to the method for preparing the cocrystal of progesterone and use thereof for increasing the thickness of endometrium, improving progesterone's solubility or increasing progesterone's permeation rate.

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Patent Owner(s)

Patent OwnerAddress
NATIONAL INSTITUTES FOR FOOD AND DRUG CONTROL100050 NO 2 WEST LANE TIANTAN BEIJING DONGCHENG DISTRICT BEIJING CITY BEIJING CITY 100050

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
He, Lan Beijing, CN 2 0
Liu, Yang Beijing, CN 1941 7962
Lu, Zhonglin Beijing, CN 3 1
Shi, Yan Beijing, CN 112 842
Wu, Xiangxiang Beijing, CN 1 0
Xiong, Jing Beijing, CN 27 88
Zhang, Na Beijing, CN 248 911
Zhu, Xin Beijing, CN 30 118

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