GLUCOSYLCERAMIDE SYNTHASE INHIBITORS

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United States of America Patent

APP PUB NO 20210261557A1
SERIAL NO

17242016

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention relates to inhibitors of glucosylceramide synthase (GCS) useful for the treatment of metabolic diseases, such as lysosomal storage diseases, either alone or in combination with enzyme replacement therapy, and for the treatment of cancer.

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Patent Owner(s)

Patent OwnerAddress
GENZYME CORPORATION450 WATER STREET CAMBRIDGE MA 02141

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
BOURQUE, Elyse Blaine, US 21 120
CABRERA-SALAZAR, Mario Framingham, US 5 24
CELATKA, Cassandra Hull, US 25 135
CHENG, Seng Natick, US 24 211
CROMWELL, Mary A Groton, US 6 27
GOOD, Andrew Wallingford, US 36 298
HIRTH, Bradford Framingham, US 14 88
JANCSICS, Katherine Wilmington, US 9 53
LEONARD, John P Manchester, US 19 131
LI, Lingyun Waltham, US 25 139
LILLIE, James Wellesley, US 21 286
LIU, Hanlan Lexington, US 20 72
MAKINO, Elina Winchester, US 14 56
MARSHALL, John Hopedale, US 331 5430
MASON, Paul Natick, US 61 359
METZ, Markus Waltham, US 55 269
MORSHED, Fazeela Waltham, US 6 36
O'SHEA, Thomas Wellesley, US 7 50
SCHEULE, Ronald Hopkinton, US 5 24
SKERLJ, Renato West Newton, US 47 518
WANG, Bing Newton, US 403 3504
XIANG, Yibin Dracut, US 39 565
ZHAO, Zhong Wayland, US 40 480

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