MICROSPHERES AND METHOD FOR PRODUCING THEM
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United States of America Patent
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Aug 26, 2021
app pub date -
Mar 8, 2021
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Sep 11, 2016
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Abstract
An organic solvent-free method for producing a plurality of microsphere having an average diameter of less than 500 μm in diameter and having average contact angle θc greater than 140°, consisting essentially of a biocompatible hot-melt carrier vehicle and a payload substance to be delivered, comprising;
- melting and mixing a polymer carrier vehicle which is solid at room temperature and at least one payload substance, anddispensing microportions of the molten mixture through a droplet-forming space onto a cooled solid superoleophobic surface.
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