USE OF SALIDROSIDE AND DERIVATIVE THEREOF IN PREPARATION OF INHIBITOR MEDICAMENT FOR DISEASES OF OPHTHALMIC FIBROSIS CAUSED BY ABNORMALITIES OF EXTRACELLULAR MATRIX PROTEINS

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United States of America Patent

APP PUB NO 20210260091A1
SERIAL NO

17252265

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Abstract

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The present invention provides use of salidroside and a derivative thereof in preparation of an inhibitor medicament for treating diseases, such as opthmalmic fibrosis, caused by abnormalities of extracellular matrix proteins. The present invention treats and prevents diseases associated with ocular fibrosis such as glaucoma, by inhibiting the expression of extracellular matrix proteins in the eye to prevent fibrosis. The present invention further provides use of an inhibitor medicament for treating and preventing diseases, such as opthmalmic fibrosis, caused by abnormalities of extracellular matrix proteins, the inhibitor medicament comprising an effective amount of salidroside and a derivative thereof as active ingredients.

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Patent Owner(s)

Patent OwnerAddress
SHANGHAI NINTH PEOPLE'S HOSPITAL SHANGHAIJIAOTONG UNIVERSITY SCHOOL OF MEDICINE639 ZHIZAOJU ROAD HUANGPU QU SHANGHAI 200011

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
FAN, Xianqun Shanghai, CN 2 1
FAN, Yuchen Shanghai, CN 10 17
GUO, Li shanghai, CN 219 3686
GUO, Tao Shanghai, CN 115 1102
Pang, Iok-Hou Shanghai, CN 51 338
WEI, Jiahong Shanghai, CN 16 227

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