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• 15 United States
• 10 France
• 8 Japan
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Patent Owner(s)

Patent Owner	Address
SHAW & SONS INC	829 W 17TH STREET SUITE 5 COSTA MESA CA 92627

International Classification(s)

• B24B:MACHINES, DEVICES, OR PROCESSES FOR GRINDING OR PO....
• C04B:LIME; MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREO....
• B28B:SHAPING CLAY OR OTHER CERAMIC COMPOSITIONS, SLAG O....
• E04C:STRUCTURAL ELEMENTS; BUILDING MATERIALS
• E04F:FINISHING WORK ON BUILDINGS, e.g. STAIRS, FLOORS

• 2021 Application Filing Year
• B24B Class
• 635 Applications Filed
• 250 Patents Issued To-Date
• 39.38 % Issued To-Date

Inventor(s)

Inventor Name	Address	# of filed Patents	Total Citations
Shaw, Ronald D	Costa Mesa, US	172	2262
# of filed Patents : 172 Total Citations : 2262

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Full Text

US Patent Application No: 2013/0281,513

siRNA FOR INHIBITION OF Hif1alpha EXPRESSION AND ANTICANCER COMPOSITION CONTAINING THE SAME

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Abstract

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Disclosed are small interfering RNA (siRNA) that complementarily binds to a base sequence of Hif1α mRNA transcript, thereby inhibiting expression of Hif1α without inducing immune responses, and a use of the siRNA for prevention and/or treatment of cancer. Since Hif1α is commonly overexpressed in almost all cancer cells, the siRNA that complementarily binds to Hif1α-encoding mRNA may inhibit expression of Hif1α through RNA-mediated interference (RNAi), thereby inhibiting proliferation and metastasis of cancer cells, and thus, the siRNA may be useful as an anticancer agent.

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Description

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