ENGINEERED CELLS WITH MODIFIED HOST CELL PROTEIN PROFILES

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United States of America Patent

APP PUB NO 20210238628A1
SERIAL NO

17052609

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Abstract

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Mammalian cell lines genetically engineered to have reduced or eliminated expression of specific host cell proteins, and methods for using the engineered mammalian cell lines for the production of recombinant proteins having low levels of residual host cell protein contamination.

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Patent Owner(s)

Patent OwnerAddress
SIGMA ALDRICH CO LLC3050 SPRUCE STREET ST LOUIS MO 63103 US

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Borgschulte, Trissa St. Charles, US 5 4
Kayser, Kevin St. Louis, US 8 21
Mascarenhas, Joaquina St. Louis, US 6 16

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