PRODUCING RECOMBINANT PROTEINS WITH REDUCED LEVELS OF HOST CELL PROTEINS
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United States of America Patent
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Issued Date -
Aug 5, 2021
app pub date -
May 3, 2019
filing date -
May 4, 2018
priority date (Note) -
Published
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Abstract
Processes for producing recombinant proteins having low levels of residual host cell proteins. The processes comprise utilizing engineered host cell lines in which specific host cell proteins are tagged with purification tags, wherein the purification tags can be used to remove those specific host cell proteins from the recombinant proteins.

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Patent Owner(s)
Patent Owner | Address | |
---|---|---|
SIGMA ALDRICH CO LLC | 3050 SPRUCE STREET ST LOUIS MO 63103 US |
International Classification(s)

- [Classification Symbol]
- [Patents Count]
Inventor(s)
Inventor Name | Address | # of filed Patents | Total Citations |
---|---|---|---|
Borgschulte, Trissa | St. Charles, US | 5 | 4 |
Kayser, Kevin | St. Louis, US | 8 | 21 |
Mascarenhas, Joaquina | St. Louis, US | 6 | 16 |
Swartzwelder, Frank | St. Louis, US | 1 | 0 |
Zillmann, Martin | Shewsbury, US | 15 | 192 |
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