PRODUCING RECOMBINANT PROTEINS WITH REDUCED LEVELS OF HOST CELL PROTEINS

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United States of America Patent

APP PUB NO 20210238222A1
SERIAL NO

17052624

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Abstract

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Processes for producing recombinant proteins having low levels of residual host cell proteins. The processes comprise utilizing engineered host cell lines in which specific host cell proteins are tagged with purification tags, wherein the purification tags can be used to remove those specific host cell proteins from the recombinant proteins.

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Patent Owner(s)

Patent OwnerAddress
SIGMA ALDRICH CO LLC3050 SPRUCE STREET ST LOUIS MO 63103 US

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Borgschulte, Trissa St. Charles, US 5 4
Kayser, Kevin St. Louis, US 8 21
Mascarenhas, Joaquina St. Louis, US 6 16
Swartzwelder, Frank St. Louis, US 1 0
Zillmann, Martin Shewsbury, US 15 192

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