SULFUR-CONTAINING GLYCANS AND POLYSACCHARIDES AND METHODS OF CHEMOENZYMATIC SYNTHESIS THEREOF
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Jul 29, 2021
app pub date -
May 24, 2019
filing date -
Jun 4, 2018
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Abstract
Described herein are sulfur-containing glycosaminoglycans, and methods of making and using them. For example, heparosan and hyaluronan analogs are described which incorporate one or more sulfur-containing sugar units that include one or more free sulfhydryls and/or one or more thio-glycosidic linkages. In some embodiments, the glycosaminoglycans are included in pharmaceutical or bioadhesive compositions.
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