METHODS OF MODULATING M2 MACROPHAGE POLARIZATION AND USE OF SAME IN THERAPY
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United States of America Patent
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Jun 17, 2021
app pub date -
Feb 24, 2021
filing date -
Aug 24, 2018
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Abstract
A method of treating a disease or disorder that can benefit from increasing an M2/M1 macrophage ratio in a subject in need thereof is provided. The method comprising: (a) culturing basophils in the presence of IL33 and/or GM-SCF; and (b) administering to the subject a therapeutically effective amount of the basophils following the culturing, thereby treating the disease or disorder that can benefit from increasing an M2/M1 macrophage ratio in the subject.
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