Benzimidazolone derived inhibitors of BCL6

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United States of America Patent

PATENT NO 12110286
APP PUB NO 20210147382A1
SERIAL NO

16616901

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Abstract

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The present invention relates to compounds of Formula I that function as inhibitors of BCL6 (B-cell lymphoma 6) activity: wherein X1, X2, R1, R2 and R3 are each as defined herein. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of proliferative disorders, such as cancer, as well as other diseases or conditions in which BCL6 activity is implicated.

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Patent Owner(s)

  • CANCER RESEARCH TECHNOLOGY LIMITED; THE INSTITUTE OF CANCER RESEARCH

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  • [Patents Count]

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bellenie, Benjamin Richard London, GB 11 17
Carter, Michael K London, GB 6 95
Cheung, Kwai Ming Jack London, GB 5 9
Davis, Owen Alexander London, GB 6 9
Hoelder, Swen London, GB 26 92
Innocenti, Paolo London, GB 11 55
Lloyd, Matthew Garth London, GB 5 9
Varela, Rodriguez Ana London, GB 1 6
Woodward, Hannah London, GB 11 55

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