INTRACELLULAR DELIVERY OF BIOMOLECULES TO INDUCE TOLERANCE
Number of patents in Portfolio can not be more than 2000
United States of America Patent
Stats
-
N/A
Issued Date -
May 13, 2021
app pub date -
May 3, 2017
filing date -
May 3, 2016
priority date (Note) -
Published
status (Latency Note)
Importance
Abstract
The present invention provides methods for inducing tolerance or suppressing an immune response to an antigen by passing a cell suspension containing an immune cell through a constriction, wherein the constriction deforms the cell thereby causing a perturbation of the cell such that an antigen and/or tolerogenic factor enters the cell, thereby generating a tolerogenic and/or immunosuppressive immune cell. In some embodiments, the tolerogenic and/or immunosuppressive immune cell is delivered to an individual and presentation of the antigen induces tolerance and/or suppresses an immune response to the antigen.
First Claim
Family
International Classification(s)
Cited Art Landscape
Patent Citation Ranking
Recipient Email Address
Recipient Email Address
Comment
Recipient Email Address
Add to Portfolio(s)
To add this patent to one, or more, of your portfolios, simply click the add button.
This Patent is in these Portfolios:
Add to additional portfolios:
Last Refreshed On:
Changes done successfully