TRPV3 AGONISTS FOR THE TREATMENT OF SKIN CONDITIONS
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United States of America Patent
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May 13, 2021
app pub date -
Dec 11, 2020
filing date -
Sep 14, 2012
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Abstract
Described are methods and uses of TRPV3 agonists for the treatment of conditions associated with TRPV3 pathophysiology such as acne, psoriasis, dermatitis, would healing, the inhibition of hair growth, anxiety or depression. Peptides comprising all or part of the C-terminal portion of soricidin are shown to activate TRPV3 cation channel activity and/or promote wound healing in keratinocytes.
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